John D Pickard Selected Research

Craniocerebral Trauma (Head Injury)

12/2021	Metabolic derangements are associated with impaired glucose delivery following traumatic brain injury.
7/2017	Focally perfused succinate potentiates brain metabolism in head injury patients.
3/2013	Optimal cerebral perfusion pressure: are we ready for it?
8/2012	Transcranial Doppler pulsatility index: what it is and what it isn't.
8/2012	Continuous determination of optimal cerebral perfusion pressure in traumatic brain injury.
1/2012	A microdialysis study of oral vigabatrin administration in head injury patients: preliminary evaluation of multimodality monitoring.
7/2011	Validation of reference tissue modelling for [11C]flumazenil positron emission tomography following head injury.
1/2009	Reactivity of brain tissue oxygen to change in cerebral perfusion pressure in head injured patients.
1/2009	A combined microdialysis and FDG-PET study of glucose metabolism in head injury.
1/2008	Nitric oxide in acute brain injury: a pilot study of NO(x) concentrations in human brain microdialysates and their relationship with energy metabolism.

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John D Pickard Research Topics

Disease

30	Traumatic Brain Injuries (Traumatic Brain Injury) 12/2021 - 04/2004
23	Craniocerebral Trauma (Head Injury) 12/2021 - 06/2002
9	Subarachnoid Hemorrhage (Aneurysmal Subarachnoid Hemorrhage) 07/2009 - 06/2002
6	Intracranial Hypertension 01/2022 - 05/2010
5	Brain Injuries (Brain Injury) 01/2008 - 12/2002
4	Contusions 10/2015 - 11/2003
3	Ischemia 01/2020 - 02/2004
3	Hypocapnia 01/2012 - 06/2004
3	Brain Ischemia (Cerebral Ischemia) 10/2007 - 02/2007
3	Hyperventilation 02/2007 - 02/2002
2	Consciousness Disorders 01/2021 - 10/2019
2	Acromegaly 11/2016 - 03/2013
2	Pituitary Neoplasms (Pituitary Adenoma) 11/2016 - 03/2013
2	Persistent Vegetative State (Vegetative State) 01/2016 - 08/2007
2	Neoplasms (Cancer) 01/2015 - 03/2013
2	Hypotension (Low Blood Pressure) 03/2013 - 06/2002
2	Hypertension (High Blood Pressure) 03/2013 - 01/2012
2	Infections 08/2012 - 10/2009
2	Wounds and Injuries (Trauma) 05/2012 - 10/2007
2	Closed Head Injuries 11/2010 - 02/2007
2	Hyperemia 01/2010 - 02/2004
2	Cerebral Infarction 07/2009 - 06/2002
2	Intracranial Vasospasm 07/2009 - 08/2005
2	Carotid Artery Diseases 07/2004 - 12/2002
1	Unconsciousness (Loss of Consciousness) 10/2019
1	Attention Deficit Disorder with Hyperactivity (Attention Deficit Hyperactivity Disorder) 01/2019
1	Mitochondrial Diseases (Mitochondrial Disease) 07/2017
1	Edema (Dropsy) 10/2015
1	Cushing Syndrome 10/2015
1	Amyloid angiopathy 01/2014
1	Acoustic Neuroma (Acoustic Neurinoma) 12/2013
1	Headache Disorders (Headache Syndromes) 12/2013
1	Huntington Disease (Huntington's Disease) 06/2013
1	Atrophy 06/2013
1	Apnea 03/2013
1	Acute Subdural Hematoma 01/2013
1	Intracranial Hemorrhages (Intracranial Hemorrhage) 08/2012
1	Hypercapnia 04/2011
1	Necrosis 02/2011

Drug/Important Bio-Agent (IBA)

15	6-chloro-2-(1-piperazinyl)pyrazine (CPP)IBA 03/2013 - 11/2003
13	Oxygen (Dioxygen)IBA 01/2020 - 06/2002
7	Glucose (Dextrose)FDA LinkGeneric 12/2021 - 06/2002
5	Carbon DioxideIBA 01/2020 - 06/2002
5	Lactic Acid (Lactate)FDA LinkGeneric 07/2017 - 01/2008
4	Biomarkers (Surrogate Marker)IBA 10/2019 - 02/2011
4	Pyruvic Acid (Pyruvate)IBA 07/2017 - 01/2008
4	Interleukin-1 Receptors (Interleukin 1 Receptor)IBA 01/2016 - 10/2007
4	Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA 12/2008 - 08/2005
4	Pravastatin (Pravachol)FDA LinkGeneric 12/2007 - 08/2005
3	Oxygen-15IBA 12/2021 - 01/2006
3	Methylphenidate (Ritalin)FDA LinkGeneric 01/2021 - 01/2018
3	CytokinesIBA 01/2016 - 10/2007
3	Glutamic Acid (Glutamate)FDA Link 01/2008 - 06/2002
2	Propofol (Diprivan)FDA LinkGeneric 10/2019 - 08/2003
2	LigandsIBA 03/2013 - 05/2002
1	Fluorodeoxyglucose F18 (Fludeoxyglucose F 18)FDA Link 12/2021
1	Anesthetics (Anesthetic Agents)IBA 01/2021
1	Dopamine Agonists (Dopamine Agonist)IBA 01/2021
1	Succinic Acid (Succinate)IBA 07/2017
1	BarbituratesIBA 01/2016
1	ChemokinesIBA 01/2016
1	EnzymesIBA 10/2015
1	Matrix Metalloproteinases (MMPs)IBA 10/2015
1	Adrenocorticotropic Hormone (ACTH)FDA Link 10/2015
1	TritiumIBA 01/2014
1	CarbonIBA 01/2014
1	2- (4'- (methylamino)phenyl)- 6- hydroxybenzothiazole (Pittsburgh compound B)IBA 01/2014
1	Amyloid (Amyloid Fibrils)IBA 01/2014
1	Somatostatin Receptors (Somatostatin Receptor)IBA 03/2013
1	Insulin-Like Growth Factor I (IGF-1)IBA 03/2013
1	P 11 (P-11)IBA 03/2013
1	lanreotide (Somatuline)FDA Link 03/2013
1	Coloring Agents (Dyes)IBA 08/2012
1	SilverIBA 08/2012
1	iodoantipyrineIBA 05/2012
1	Vigabatrin FDA Link 01/2012
1	Neuroprotective AgentsIBA 01/2012
1	Flumazenil (Romazicon)FDA LinkGeneric 07/2011
1	Chemokine CCL5IBA 02/2011
1	platelet-derived growth factor AIBA 02/2011
1	Platelet-Derived Growth FactorIBA 02/2011
1	CD40 Ligand (CD40L)IBA 02/2011
1	Interleukin-8 (Interleukin 8)IBA 02/2011
1	Macrophage Inflammatory Proteins (Macrophage Inflammatory Protein 1)IBA 02/2011
1	InterleukinsIBA 02/2011
1	Hemoglobins (Hemoglobin)IBA 11/2010
1	3,4,4a,10b- tetrahydro- 4- propyl- 2H,5H- (1)benzopyrano(4,3- b)- 1,4- oxazin- 9- olIBA 01/2010
1	Anti-Bacterial Agents (Antibiotics)IBA 10/2009
1	4,4'- Diisothiocyanostilbene- 2,2'- Disulfonic Acid (DIDS)IBA 07/2009
1	Erythropoietin FDA Link 07/2009

Therapy/Procedure

12	Therapeutics 11/2016 - 02/2002
6	Decompressive Craniectomy 01/2022 - 06/2011
6	Catheters 08/2012 - 01/2008
5	Critical Care (Surgical Intensive Care) 12/2021 - 01/2006
3	Radiotherapy 11/2016 - 02/2008
2	Craniotomy 01/2022 - 09/2012
2	Stents 12/2013 - 02/2008
1	Transplantation 06/2013
1	Cell Transplantation 06/2013
1	Lasers (Laser) 05/2010